| 1. | The inhibitory effect of tlsfjm on rat cardiac allograft rejection 抑制大鼠心脏移植排斥反应的作用 |
| 2. | A sensitive predictor of renal allograft rejection : two - hour post - dose blood concentration of cyclosporine a 血药浓度是预测移植肾排异反应的敏感指标 |
| 3. | Preious work has suggested that heat shock protein ( hsp ) - 70 is associated with acute allograft rejection 先前的工作表明热休克蛋白( hsp ) - 70与急性同种异体排斥反应相关。 |
| 4. | Effects of ethanol extract of sinomenium acutum on acute cardiac allograft rejection and peripharal levels of il - 2 and il - 10 in rats 雷洛昔芬对去卵巢大鼠骨组织雌激素受体亚型表达的影响 |
| 5. | Conclusions dgf with the occurrence of allograft rejection episodes would significantly affects the long - term outcome . so , efforts should be made to improve the initial graft function 结论移植肾功能延迟恢复明显降低受者的远期效果,必须努力改善移植肾的初期功能状态。 |
| 6. | Allograft rejection remains to be the rnain obstacle of translanation medicine . whh the development of twungenetics , we have deepened our anowledge on immnological mecbosms underlying toplanation rejection . the application of csa to clinical use greatly reduced the morbidity of rejections and toroved the outcome oftraxisplanation 由于器官移植受者需要终身使用免疫抑制药物,这些非特异性的免疫抑制剂,在控制移植物排斥反应的同时,又不可避免的导致感染的频繁发生和恶性肿瘤发病率的升高,时刻威胁受者的生命安全,成为影响受者长期生存和生活质量的主要因素。 |
| 7. | In terms of regulatory t cell , cd4 + cd25 + t cell is representitive . ln naive individuals , cd4 + cd25 + t cells function as self tolerance , in recipients with long term survival allograft . they play an important role in suppression of allograft rejection . immune regulation potent cd4 + cd25 + t cells can be recovered from recipients with long term survival allografts . such regulatory t cells can suppress t cell mediated rejection in vitro and in vivo 其中, cd4 + cd25 + t细胞是具有代表性的调节性t细胞。在未经处理的机体内, cd4 + cd25 + t细胞对保持自身耐受起着关键的作用。在同种异体移植物长期存活的受体内, cd4 + cd25 + t细胞对抑制同种异体移植物排斥反应也起到很重要的作用。 |
| 8. | Transplantation has been developed to an effctive strategy for treatment of end stage diseases of multiple organs since 1950 ' s . despite success of current immunosuppressive drugs , transplantation immunologists and surgeons are still seeking to achieve tolerance to allograft . there are several different mechanisms such as clonal deletion , anergy , neglect , immuno regulation . which maintain tolerance to self - antigen . some strategies , derived from these mechanisms has been proved to be encouraged in suppression of allograft rejection 二十世纪五十年代以来,器官移植的进展使同种异体器官移植成为治疗多种器官终末期疾病的有效手段。尽管目前免疫抑制方案非常有效,但免疫耐受仍是移植免疫学家和外科医生关注的课题。有多个机制使免疫系统对自身抗原保持耐受,如:克隆清除、忽略、失能、免疫调节。 |